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also smoke the leaves.
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Compulsive use has been reported among drug users who inject opioids and those who use opioids to manage pain without direction from medical professionals. Chronic users have also reported withdrawal symptoms including irritability runny nose and diarrhea. Withdrawal is generally short-lived and mild and it may be effectively treated with dihydrocodeine and lofexidine. Other drugs were used in all cases and in one kratom was speculated to possibly be the primary cause of death. O-Desmethyltramadol the active metabolite of the prescription drug tramadol. Possession of kratom leaves is illegal in Thailand. August 3 1943 which made planting the tree illegal and required existing trees to be cut down.
Effects of the extracts from Mitragyna speciosa Korth. Hassan Z Muzaimi M Navaratnam V Yusoff NH Suhaimi FW Vadivelu R et al. McWhirter L Morris S; Morris (2010).
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